Indo-1 Near Membrane (NearMem)

  • #0127  Indo-1 NearMem (AM) 1mg... Discontinued
  • #0128  Indo-1 NearMem (AM) 20 x 50 ug... $130 Add to Cart
  • #0129  Indo-1 NearMem (salt) 1 mg... $110 Add to Cart

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Unlike other hydrophobic dyes, TEFLabs near membrane dyes have a piperazine collar to latch the dye into the membrane, leaving the chelating portion to measure calcium in the gates. Our near-membrane UV-excitable indicators Fura-2 NearMem (formerly FFP-18) , and Indo-1 NearMem  (formerly FIP-18), have enjoyed considerable success for their applications, because unlike other hydrophobic indicators, they do not get lost in the membrane.

Indo-1 is also available in High Affinity (Indo-1), Low Affinity (Indo-1 LowAff), and Leakage Resistant (Indo-1 LeakRes) versions.

DATA

Excitation: 346 nm

Emission:  ratiometric,  475 nm and 405 nm

kd: 450 nM

Solubility: H20 (salt form)  DMSO (AM form)

Molecular Weight:  1134 g/mol (salt), 840 g/mol (AM)

RESULTS

Indo-1 NearMem (FIP-18)

FIG. 6.10 Indo-1 NearMem (FIP-18)

 

RELATED PRODUCTS

Indo-1

Indo-1 LeakRes

Indo-1 LowAff

Asante Calcium Red Near Membrane

 

Fluo-2 Near Membrane

Fura-2 Near Membrane