Fluo-2

Fluo-2 (Medium Affinity, kd:390 nM) has been found to be much brighter (1.5x) than Fluo-4 in cellular experiments. The increased brightness of Fluo-2  is partly attributable to its superior loading in most cell types. Loading can be performed at room temperature.

Fluo-2 Data

  • Excitation: 488 nm
  • Emission: 515 nm
  • kd: 390 nM
  • Solubility: H20 (salt form) DMSO (AM form)
  • Molecular Weight: 877 g/mol (salt) 1047 g/mol (AM)

Documents

Spec Sheets
Info Pack

Fluo-2 Overview

The increased brightness of Fluo-2 MedAff is partly attributable to its superior loading in most cell types. Although a lower pKa was assumed necessary when the Fluo dyes were invented, experimental data has established that Fluo-2’s pKa is not a limitation.

Since the patent covering the Fluo-2 molecule has expired, and royalties are no longer due to its inventors, Fluo-2 has increasingly been used under a variety of private label names, including Fluo-8, as the dye of choice for many of the most popular calcium assay kits.

TEFLabs' Fluo-2 offers a brighter, faster, and cheaper direct substitue to Fluo-4 due to its greater fluorescent enhancement, faster and easier room temperature loading, and significantly reduced price point compared to Fluo-4 (as well as other Fluo dyes).

Read More

Fluo-2 Catalog Numbers

Loading