ACR Low Affinity Data
- Excitation: 488 nm
- Emission: 525/650 nm
- kd: 6.65 µM
- Solubility: H20 (salt form) DMSO (AM form)
- Molecular Weight: 1000g/mol (salt) 1200 g/mol (AM)
ACR LowAff Overview
Unlike other hydrophobic dyes, TEFLabs near membrane dyes have a piperazine collar to latch the dye into the membrane, leaving the chelating portion to measure calcium in the gates. Our near-membrane UV-excitable indicators Fura-2 NearMem (formerly FFP-18), and Indo-1 NearMem (formerly FIP-18), have enjoyed considerable success for their applications, because unlike other hydrophobic indicators, they do not get lost in the membrane.