Product Specification and Analysis

 

 

PRODUCT NAME:

FLUO-3 (AM)

LOT:

 

 

C51H50Cl2N2O23

 

M.W. 1129.86 g/mol

 

Kd = 390 nM (After hydrolysis)*

 

Store Frozen (-20°C)

 

PROTECT FROM LIGHT

 

Soluble in DMSO

CAS Number/Name:

121714-22-5 Glycine, N-[4-[6-[(acetyloxy)methoxy]-2,7-dichloro-3-oxo-3H-xanthen-9-yl]-2-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxyethyl]amino]-5-methylphenoxy]ethoxy]phenyl]-N-[2-[(acetyloxy)methoxy]-2-oxyethyl]-, (acetyloxy)methyl ester

 

DESCRIPTION:

 

Red solid. Cell-permeable acetoxymethyl ester (AM) derivative of Fluo-3 with spectral properties similar to the parent compound. Insensitive to magnesium.

 

CATALOG NUMBER:

 

0116 AND 0117

 

APPEARANCE:

 

Orange Red Glossy Solid

 

TLC :

 

Ethyl Acetate: Hexane 2:1

Rf = 0.4

Purity:  100%

 

ABSORPTION SPECTRUM:

 

l max:   459 nm (Ethyl Acetate)

Extinction: 25,000 M-1cm-1

 

EMISSION SPECTRUM:

 

lmax:  526 nm (after hydrolysis)*

 

EXCITATION:

 

490-510 nm (after hydrolysis)*

 

HPLC:

Solvent System:

Column:

 

Purity: >95%

Water/MeOH gradient 40-100%

C18

* Fluorescence and binding to calcium is only observed after hydrolysis to the Fluo-3 cation.