Product Specification and Analysis

Product Specification and Analysis

N-(6-methoxy-8-quinolyl)-p-toluenesulfonamide
PRODUCT NAME:	TSQ

	C₁₇H₁₇N₂O₃S
	M.W. 329.4 g/mol
	Store Frozen (-20°C)
	PROTECT FROM LIGHT
	Soluble in EtOH
DESCRIPTION:	Yellow powder. Zn²⁺ probe selective in the presence of Mg²⁺ and Ca²⁺.
CATALOG NUMBER:	0010
APPEARANCE:	Yellow powder
TLC :	Chloroform: MeOH Purity: 100%
ABSORPTION SPECTRUM:	l max : 334 nm Extinction: 4,200 M^-1cm^-1
EMISSION:	l max : 485 nm

References

1.Characterization of N-(6-methoxy-8-quinolyl)-p-toluenesulfonamide for the

detection of zinc in living sperm cells.

Andrews JC, Nolan JP, Hammerstedt RH, Bavister BD

Cytometry 1995 Oct 1 21:2 153-9.

2. The in vitro ejection of zinc from human immunodeficiency virus (HIV) type

1 nucleocapsid protein by disulfide benzamides with cellular anti-HIV

activity.

Tummino PJ, Scholten JD, Harvey PJ, Holler TP, Maloney L, Gogliotti R,

Domagala J, Hupe D

Proc Natl Acad Sci U S A 1996 Feb 6 93:3 969-73.

3. The use of TSQ as an islet-specific stain for purification of islets by

fluorescence-activated sorting.

Jindal RM, Gray DW, Morris PJ

Transplantation 1993 Nov 56:5 1282-4.

4. Zinc-containing 7S-NGF complex. Evidence from zinc histochemistry for

localization in salivary secretory granules.

Frederickson CJ, Pérez-Clausell J, Danscher G

J Histochem Cytochem 1987 May 35:5 579-83.

5. Possible role of zinc in the selective degeneration of dentate hilar neurons

after cerebral ischemia in the adult rat.

Tonder N, Johansen FF, Frederickson CJ, Zimmer J, Diemer NH

Neurosci Lett 1990 Feb 16 109:3 247-52.

6. A new method for quantification of islets by measurement of zinc content.

Jindal RM, Taylor RP, Gray DW, Esmeraldo R, Morris PJ

Diabetes 1992 Sep 41:9 1056-62.

7. Zinc-specific N-(6-methoxy-8-quinolyl)-para-toluenesulfonamide as a

selective nontoxic fluorescence stain for pancreatic islets.

Jindal RM, Gray DW, McShane P, Morris PJ

Biotech Histochem 1993 Jul 68:4 196-205.

8. A fluorescence method to determine picomole amounts of Zn(II) in

biological systems.

Reyes JG, Santander M, Martinez PL, Arce R, Benos DJ

Biol Res 1994 27:1 49-56.

9. Role of zinc during hamster sperm capacitation.

Andrews JC, Nolan JP, Hammerstedt RH, Bavister BD

Biol Reprod 1994 Dec 51:6 1238-47.

10. Hypochlorous acid mobilizes intracellular zinc in isolated rat heart myocytes.

Tatsumi T, Fliss H

J Mol Cell Cardiol 1994 Apr 26:4 471-9.

11. Ca2+ and Zn2+ dependence of DNA synthesis in untransformed and in

Ha-ras(val-12)-expressing NIH 3T3 cells.

Back CJ, Sistonen L, Enkvist MO, Heikkilä JE, Akerman KE

Exp Cell Res 1993 Sep 208:1 303-10.